Cancer cells can treat tumors

Cancer cells can treat tumors.


New scrutiny suggests that many cancer cells are equipped with a generous of suicide pill: a protein on their surfaces that gives them the gift to discharge an "eat me" outstanding to immune cells. The contest now, the researchers say, is to conspicuous out how to coax cancer cells into emitting the communicate rather than a dangerous "don't eat me" signal tretinoin pharmacy. A swot published online Dec 22 2010 in Science Translational Medicine reports that the cells propel out the enticing "eat me" wink by displaying the protein calreticulin.



But another molecule, called CD47, allows most cancer cells to elude rack and ruin by sending the antithetical signal: "Don't feed-bag me". In earlier research, Stanford University School of Medicine scientists found that an antibody that blocks CD47 - turning off the wave - could assistance scrimmage cancer, but mysteries remained. "Many general cells in the body have CD47, and yet those cells are not distressed by the anti-CD47 antibody," Mark Chao, a Stanford bachelor apprentice and the study's lead author, said in a university talk release.