Treatment Of Diabetes Is Different For Men And Women

Treatment Of Diabetes Is Different For Men And Women.
Widely second-hand diabetes drugs have abundant junk on men's and women's hearts, a unusual look at suggests. Researchers examined how three commonly prescribed treatments for variety 2 diabetes false 78 patients who were divided into three groups. One bunch took metformin alone, the duplicate group took metformin added rosiglitazone (sold under the trade-mark name Avandia) and the third group took metformin extra Lovaza, a type of fish oil recommended reading. Metformin reduces blood sugar origination by the liver and improves insulin sensitivity.

Rosiglitazone also improves insulin kind-heartedness and moves honest fatty acids out of the blood. Lovaza lowers blood levels of another prototype of paunchiness called triglycerides. The researchers found that the drugs had very bizarre and every so often opposite effects on the hearts of men and women, even as the drugs controlled blood sugar equally well in both genders. The examination appears in the December dissemination of the American Journal of Physiology - Heart and Circulatory Physiology.

Although metformin had arrogant sensitivity property in women, it caused the callousness metabolism of men to burn less sugar and more fats. Chronic raging of fat by the hub results in harmful changes that can lead to sympathy failure, said the researchers, from the Washington University School of Medicine in St Louis. "Instead of making kindness metabolism more typical in men, metformin peerless made it worse, looking even more congenial a diabetic heart," study older author Dr Robert Gropler said in a university rumour release.

And "But in women, metformin had the desired sense - lowering portly metabolism and increasing glucose understanding by the heart". Taking either rosiglitazone or Lovaza with metformin seemed to set some of the negative heart crap of metformin alone in men. Taking rosiglitazone in summation to metformin further improved women's generosity metabolism, compared to taking metformin alone.

The reckoning of Lovaza to metformin did not have a strong effect either point for men or women, the researchers said. "Our contemplation suggests that we need to better define which therapies are optimal for women with diabetes and which ones are optimal for men," said Gropler, a professor of radiology. The lucubrate did not, however, demonstrate a cause-and-effect relate between the narcotize combinations and compassion changes extra cheap resveratrol ultima. It showed only an association.