Treatment Of Diabetes Is Different For Men And Women

Treatment Of Diabetes Is Different For Men And Women.
Widely utilized diabetes drugs have unconventional crap on men's and women's hearts, a unfledged cram suggests. Researchers examined how three commonly prescribed treatments for paradigm 2 diabetes awkward 78 patients who were divided into three groups. One place took metformin alone, the next group took metformin added rosiglitazone (sold under the brand name name Avandia) and the third group took metformin bonus Lovaza, a type of fish oil hypercet.herbalhat.com. Metformin reduces blood sugar casting by the liver and improves insulin sensitivity.

Rosiglitazone also improves insulin irritability and moves unconditional fatty acids out of the blood. Lovaza lowers blood levels of another fount of wealthy called triglycerides. The researchers found that the drugs had very novel and once in a while opposite effects on the hearts of men and women, even as the drugs controlled blood sugar equally well in both genders. The investigation appears in the December matter of the American Journal of Physiology - Heart and Circulatory Physiology.

Although metformin had utilitarian heartlessness things in women, it caused the quintessence metabolism of men to burn less sugar and more fats. Chronic flaming of fat by the nitty-gritty results in harmful changes that can lead to goodness failure, said the researchers, from the Washington University School of Medicine in St Louis. "Instead of making hub metabolism more stable in men, metformin abandoned made it worse, looking even more get a bang a diabetic heart," study superior author Dr Robert Gropler said in a university story release.

And "But in women, metformin had the desired effectuate - lowering paunchy metabolism and increasing glucose perspicaciousness by the heart". Taking either rosiglitazone or Lovaza with metformin seemed to bring down some of the negative heart goods of metformin alone in men. Taking rosiglitazone in ell to metformin further improved women's centre metabolism, compared to taking metformin alone.

The reckoning of Lovaza to metformin did not have a strong effect either disposition for men or women, the researchers said. "Our workroom suggests that we need to better define which therapies are optimal for women with diabetes and which ones are optimal for men," said Gropler, a professor of radiology. The on did not, however, sustain a cause-and-effect vinculum between the medicate combinations and focus changes vigrx. It showed only an association.